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A nuchal-type fibroma is a rare benign proliferation involving the dermis and subcutaneous tissues, that is a collection of dense, hypocellular bundles of collagen with entrapped adipocytes and increased numbers of small nerves. It is no longer called a nuchal fibroma, but instead a "nuchal-type fibroma" since it develops in other anatomic sites. There is no known etiology. == Signs and symptoms == These lesions are generally asymptomatic, although patients give a long history of a solitary, superficial mass. The mass is usually in the neck (hence the name "nuchal-type"), but it can be seen in the extremities, lumbosacral area, buttocks, and face. There is a strong association with diabetes mellitus and Gardner syndrome; in fact, it may be the initial manifestation of Gardner syndrome. == Pathology findings == The tumors are unencapsulated and poorly circumscribed, showing a firm, white cut surface. Most tumors are about 3.5 cm, but can be up to 8 cm. By microscopic examination, there are haphazardly arranged thick collage fibers, with a low cellularity and no pleomorphism. There are usually entrapped fat cells, skeletalmuscle, and peripheral nerves. The may be perineural fibrosis. Interestingly, the elastic fibers may be altered, which is why an elastofibroma is considered in the differential diagnosis. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Nuchal fibroma」の詳細全文を読む スポンサード リンク
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